| 摘要: |
| 目的:探讨临床药师在多重感染重症肺炎患儿治疗中的作用。方法:临床药师全程参与1 例耶氏肺孢子菌合并阴沟肠
杆菌、人类疱疹病毒5 型引起的重症肺炎患儿的诊疗过程,协助临床制定治疗方案。治疗过程中患儿反复发热,发生皮疹及肝
功能损伤等药物不良反应,药师协助医师对不良反应的关联性进行分析,重新调整抗感染治疗方案。结果:药师的建议被医师
采纳,患儿病情稳定顺利撤机(呼吸机),未再发生药物不良反应,治疗后好转出院。结论:临床药师在治疗过程中可以协助医
师根据患儿病情变化优化治疗方案,包括抗感染治疗和不良反应的关联性评价,能发挥自身的价值,提高了药师在治疗过程中
的参与度,更好地促进患儿的合理用药。 |
| 关键词: 耶氏肺孢子菌肺炎 多重感染 重症肺炎 药学监护 |
| DOI：doi:10.13407/j.cnki. jpp.1672-108X.2024.11.007 |
|
| 基金项目:基金项目:云南省科技厅科技计划项目,编号202201AY070001-220。 |
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| Pharmaceutical Practice for a Child with Severe Pneumonia with Multiple Infections Participated byClinical Pharmacists |
| Shang Feineng, Xu Jiazhong, Yang Xufen, Feng Zaili, Song Fang |
| (The Affiliated Dehong Hospital of Kunming Medical
University, Dehongzhou People’s Hospital, Yunnan Dehong 678499, China) |
| Abstract: |
| Objective: To investigate the role of clinical pharmacists in the treatment of children with severe pneumonia with multiple
infections. Methods: Clinical pharmacists participated into the diagnosis and treatment of a child with severe pneumonia induced by
Pneumocystis jirovecii ( PJ) combined with Enterobacter cloacae and human betaherpesvirus 5 ( HCMV) and assisted the clinical
formulation of treatment regimen. During the treatment, the child had repeated fever, rash and liver function injury. The pharmacists
assisted the clinicians in analyzing the correlation of adverse drug reactions and readjusted the anti-infective treatment regimen. Results:
The pharmacist’ s suggestion was adopted by the clinicians. The child was stabilized and successfully withdrawn from the machine
(ventilator), no further adverse drug reactions occurred, and was discharged from the hospital after treatment. Conclusion: Clinical
pharmacists can assist clinicians in optimizing the treatment regimen according to the changes of disease condition, including the
correlation evaluation of anti-infective treatment and adverse drug reactions, which can bring their value into play, improve the
participation of pharmacists in the therapeutic process, and better promote the rational drug use in children. |
| Key words: Pneumocystis jirovecii pneumonia multiple infections severe pneumonia pharmaceutical care |
