| 摘要: |
| 目的:探讨多种微量元素注射液(Ⅰ)[MTEI(Ⅰ)]对复杂性阑尾炎患儿术后快速康复的影响。方法:回顾性分析2020 年6 月
至2024 年6 月我院小儿外科收治的214 例复杂性阑尾炎患儿的临床资料。以是否使用MTEI(Ⅰ)分为对照组154 例[未使用
MTEI(Ⅰ)]和观察组60 例[使用MTEI(Ⅰ)],采用倾向得分匹配法校正组间混杂因素,通过Fisher 精确检验或χ2 检验比较两
组患儿治疗后的感染指标、炎症指标、胃肠功能恢复情况、手术切口感染情况、住院时间、住院费用等的变化。结果:倾向得分匹
配后共54 对配对成功,匹配后两组患儿的基线资料比较差异无统计学意义(P>0. 05);观察组术后第4 天白细胞(WBC)、中性
粒细胞(NEU)、中性粒细胞百分比(NEUR)、C-反应蛋白(CRP)水平低于对照组(P<0. 05);两组患儿胃肠道功能恢复情况比较
差异无统计学意义(P>0. 05);观察组发生手术并发症0 例,对照组6 例( P <0. 05),观察组中位住院时间5. 00 天,对照组
7. 50 天(P<0. 05),观察组中位住院费用12 066 元,对照组14 315 元(P<0. 05)。结论:MTEI(Ⅰ) 可以在手术辅以抗感染的基
础上进一步降低复杂性阑尾炎术后患儿的感染指标、炎症指标、手术并发症发生率,缩短住院时间、降低医疗成本,本研究可指
导临床医生用药,对复杂性阑尾炎患儿的术后早期康复具有重要意义。 |
| 关键词: 复杂性阑尾炎 微量元素 加速康复外科 倾向得分匹配 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2025.08.005 |
|
| 基金项目:基金项目:四川省出生缺陷临床医学研究中心重点项目,编号2019YFS0531。 |
|
| Effects of Multi-Trace Elements Injection ( Ⅰ ) on Rapid Postoperative Recovery of Children withComplicated Appendicitis |
| Li Jia, Liu Ming, Xiong Geng |
| (Affiliated Hospital of Southwest Medical University, Sichuan Luzhou 646000, China) |
| Abstract: |
| Objective: To probe into the effects of multi-trace elements injection (Ⅰ) (MTEI(Ⅰ)) on rapid postoperative recovery of
children with complicated appendicitis. Methods: A retrospective analysis was conducted on clinical data of 214 children with
complicated appendicitis admitted to the Pediatric Surgery from Jun. 2020 to Jun. 2024. Patients were divided into the control group (n =
154, without MTEI(Ⅰ)) and observation group (n = 60, with MTEI(Ⅰ)). Propensity score matching was used to adjust the
confounding variables. Changes in infection indicators, inflammatory indicators, recovery of gastrointestinal function, surgical incision
infection status, length of stay, and hospitalization cost of two groups after treatment were compared by using Fisher’s exact test or χ2
test. Results: After propensity score matching, 54 matched pairs were successfully established, with no significant differences in
baseline characteristics between two groups (P>0. 05). On the 4th day after surgery, the levels of white blood cell (WBC) count,
neutrophil count (NEU), neutrophil rate (NEUR), and C-reactive protein (CRP) in the observation group were lower than those in the
control group (P<0. 05). No significant difference was found in gastrointestinal function recovery (P>0. 05). Surgical complications
occurred in six patients in the control group but none in the observation group (P<0. 05). The median length of stay was 5. 00 d in the
observation group and 7. 50 d in the control group (P<0. 05). The median hospitalization cost in the observation group was 12,066
RMB, and that in the control group was 14,315 RMB (P<0. 05). Conclusion: Adjunctive use of MTEI(Ⅰ) alongside surgery and
anti-infective therapy further reduces infection indicators, inflammatory indicators, decreases surgical complication rates, shortens length
of stay, and lowers hospitalization cost in children with complicated appendicitis. These findings provide evidence-based guidance for
clinical practice, highlighting the role of MTEI(Ⅰ) in promoting early postoperative recovery of children with complicated appendicitis. |
| Key words: complicated appendicitis trace elements rapid recovery after surgery propensity score matching |
