| 摘要: |
| 目的:探讨母亲妊娠期糖尿病新生儿(IDMs)口服葡萄糖对血糖、胆红素及体质量的影响。方法:选取2012年10月至2015年10月在我院出生的IDMs 217例,采用数字表法分为观察组110例与对照组107例。观察组新生儿于出生30 min内即用奶瓶或鼻饲(口饲)喂10%葡萄糖5 mL/kg,间隔1~2 h 1次,生后2~3 h开奶,直至连续血糖测定2次正常。对照组以母乳喂养为主,喂养困难者辅以人工喂养。两组新生儿均于生后1 h、2 h、3 h、6 h、12 h、24 h、48 h监测血糖,统计新生儿低血糖症、胆红素值、体质量等情况。结果:两组IDMs出生后不同时间点血糖水平比较,对照组生后2 h血糖为最低值,生后3 h 为次最低值,与观察组2 h、3 h血糖值比较差异有统计学意义(P<0.05);两组生后1 h、6 h、12 h、24 h、48 h血糖值比较差异无统计学意义(P>0.05)。两组IDMs出生后1 h低血糖症发生率比较差异无统计学意义(P>0.05)。生后2 h、3 h观察组低血糖症发生率为5.5%、2.7%,对照组低血糖症发生率为26.1%、17.8%,两组比较差异有统计学意义(P<0.05)。对照组低血糖症发生率2 h最高,3 h次之,生后12 h、24 h、48 h血糖值在正常范围。对照组新生儿出生后体质量下降明显高于观察组,差异有统计学意义(P<0.05)。两组IDMs经皮胆红素测定比较,1 d日龄时胆红素水平差异无统计学意义,日龄2、3、4 d时对照组明显高于观察组,差异有统计学意义(P<0.05)。结论:IDMs生后口服葡萄糖水,可降低生后2 h、3 h低血糖症发生率,降低胆红素增长速度,减缓体质量下降。 |
| 关键词: 妊娠期 糖尿病 新生儿 血糖 胆红素 体质量 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2017.02.009 |
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| 基金项目: |
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| Influence of Oral Glucose on the Blood Glucose, Bilirubin and Weight in Infants of Diabetes Mothers |
| Zeng Baoyu |
| (Yanqing District Jingzhuang Town Community Health Service Center of Beijing, Beijing 102105, China) |
| Abstract: |
| Objective: To discuss the influence of oral glucose on the blood glucose, bilirubin and weight in infants of diabetes mothers (IDMs). Methods: By adopting the numeration table method, 217 IDMs born in our hospital from October 2012 to October 2015 were chosen and divided into the observation group and the control group. IDMs in observation group were fed with 10% glucose water at 5 mL/kg with bottles or nasal/oral feeding. Fed once per 1 to 2 hours and began nursing 2 to 3 hours till the blood glucose were tested with two successive normal values. IDMs in control group were breast-feeded mainly. Those with difficulties in breast-feeding were artificially fed. Monitored the blood glucose at 1 h, 2 h, 3 h, 6 h, 12 h, 24 h and 48 h after birth and counted the hypoglycemia, bilirubin value and weight of the newborn infants. Results: Lowest and the second lowest blood glucose were measured for the IDMs in control group at 2 h and 3 h after birth respectively, there were statistical differences in two groups (P<0.05). The comparisons of blood glucose measured at 1 h, 6 h, 12 h, 24 h and 48 h after birth for the two groups, which had no statistical differences (P>0.05). For the hypoglycemia rate at 1 h after birth, which had no statistical difference between two groups (P>0.05). The hypoglycemia rate at 2 h and 3 h after birth for the observation group and control group were 5.5%, 2.7% vs 26.1%, 17.8%, respectively (P<0.05). The highest and second highest hypoglycemia rates for the control group were occurred at 2 h and 3 h after birth, respectively. The blood glucose for newborn infants were measured in normal range at 12 h, 24 h, 48 h after birth. For the 1-day-old IDMs, the difference of bilirubin has no statistical significance in two groups (P>0.05). For 2 to 5-day-old IDMs, transcutaneous bilirubin of the control group were apparently higher than those of the observation group, with the differences of statistical significance. Conclusion: By taking glucose orally for the IDMs, the hypoglycemia rate at 2 h and 3 h after birth is decreased. The speed of bilirubin growth is decreased. And the weight loss is slowed down. |
| Key words: gestation period diabetes newborn blood glucose bilirubin weight |
