| 摘要: |
| 目的:探讨母亲甲状腺功能亢进症(甲亢)对新生儿胎龄、体质量及甲状腺功能的影响。方法:选择我院收治的90例妊娠期甲亢患者,根据其治疗方式分为试验组1和试验组2,每组45例,其中试验组1采用非抗甲状腺药物治疗,试验组2采用抗甲状腺药物治疗,比较两组患者的治疗效果。同时选取45例健康产妇,设为对照组,比较三组产妇的新生儿体质量、胎龄和性别。结果:三组新生儿体质量两两比较差异均有统计学意义(P<0.05),试验组1<试验组2<对照组,性别及胎龄比较差异无统计学意义(P>0.05)。不良妊娠结局的发生率试验组1为42.22% (19/45),试验组2为8.89%(4/45),对照组为2.22%(1/45),试验组1的不良妊娠结局发生率均明显高于试验组2及正常对照组(P<0.05)。三组TSH、FT3、FT4水平两两比较差异均有统计学意义(P<0.05),试验组1>试验组2>对照组。结论:妊娠期甲亢应用抗甲状腺药物治疗后能够改善新生儿的甲状腺功能,减少妊娠不良结局。 |
| 关键词: 甲状腺功能亢进症 新生儿 体质量 甲状腺功能 |
| DOI：doi: 10.13407/j.cnki.jpp.1672-108X.2017.11.002 |
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| 基金项目: |
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| Influence of Maternal Hyperthyroidism on Neonatal Gestational Age, Birth Weight and Thyroid Function |
| Yue bo |
| (The Second Affiliated Hospital of Qiqihar Medical School, Heilongjiang Qiqihar 161006, China) |
| Abstract: |
| Objective: To study the effect of maternal hyperthyroidism on neonatal gestational age, birth weight and thyroid function. Methods: Ninety cases with maternal hyperthyroidism of our hospital were selected, all cases were divided into the experimental group 1 and experimental group 2, 45 cases in each group. The experimental group 1 was given non-anti-thyroid medication, the experimental group 2 was given anti-thyroid medication, the effect of two groups was compared. Forty-five cases of healthy puerperae were select at the same time, as the control group, neonatal gestational age, birth weight, gender, and thyroid function of three groups were compared. Results: There were significant differences in neonatal birth weight between the three groups (P<0.05), of which the experimental group 10.05). The incidence of adverse pregnancy outcomes of experimental group 1, experimental group 2 and control group were 42.22% (19/45), 8.89% (4/45) and 2.22% (1/45) respectively, which in experimental group 1 was significantly higher than that in the experimental group 2 and control group (P<0.05). The differences of TSH, FT3 and FT4 levels between the three groups were statistically significant (P<0.05), among which the experimental group 1>experimental group 2>control group. Conclusion: The application of anti-thyroid drugs can improve the thyroid function and reduce the adverse pregnancy outcomes in pregnant women with hyperthyroidism. |
| Key words: hyperthyroidism newborn weight thyroid function |
