| 摘要: |
| 目的：探讨血清C-反应蛋白（CRP）和降钙素原（PCT）在儿童社区获得性肺炎（CAP）病情严重程度评估中的作用。方法：选取62例符合CAP诊断标准的儿童患者（CAP组）及57例体检健康的正常儿童（对照组）作为研究对象，根据儿童病情不同将CAP组分为重症组（28例）和轻症组（34例）。检测所有儿童血清中CRP及PCT水平，并进行对比分析。结果：CAP患儿的血清CRP及PCT水平分别为（12.49 ± 2.76）mg/L和（1.622 ± 0.105）ng/mL，均显著高于健康儿童的CPR和PCT水平［(5.37 ± 1.81) mg/L & (0.051 ± 0.003) ng/mL］，差异有统计学意义（t值分别为8.736、9.251，P<0.01）；重症组患儿的PCT水平为（2.445 ± 0.134）ng/mL，显著高于轻症组的（1.019 ± 0.157）ng/mL（t=8.976，P<0.01），但重症组患儿的CPR水平［(12.75 ± 2.11) mg/L］与轻症组［(12.17 ± 2.03) mg/L］比较差异无统计学意义（t=0.896，P>0.05）。结论：CAP患儿的血清CRP及PCT水平均明显升高，但应用PCT作为CAP病情严重程度评估的指标较CRP更为有效。 |
| 关键词: C-反应蛋白 降钙素原 儿童 社区获得性肺炎 病情评估 |
| DOI：doi:10.13407/j.cnki.jpp.1672-108X.2018.12.002 |
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| 基金项目: |
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| The Application of Serum C-Reactive Protein and Procalcitonin in the Severity Evaluation of Community-Acquired Pneumonia in Children |
| Tang Jingping, Gu Chengping, Huang Lieping |
| (Maternal and Child Health Hospital of Zhoushan Hospital, Zhejiang, Zhoushan 316000, China) |
| Abstract: |
| Objective: To investigate the role of serum C-reactive protein (CRP) and procalcitonin (PCT) in the severity evaluation of community-acquired pneumonia (CAP) in children. Methods: A total of 62 children patients accordant with the CAP diagnosis standard (CAP group) and a total of 57 healthy children accordant with medical examination (control group) were selected as research objects. According to patients’ condition, the CAP group were further divided into the severe group (28 cases) and the mild group (34 cases). The levels of serum CRP and PCT were detected and analyzed. Results: The levels of serum CRP and PCT in the CAP children were significantly higher than that in the healthy children (t was 8.736, 9.251, P<0.01); the level of PCT in children with severe CAP was obviously higher than that in children with mild CAP (t=8.976, P<0.01), while the level of CRP was not significantly different between children with severe CAP and children with mild CAP (t=0.896, P>0.05). Conclusion: The levels of serum CRP and PCT both rise obviously in CAP children, but PCT is a better indicator than CRP in the severity evaluation in children with CAP. |
| Key words: C-reactive protein procalcitonin children community-acquired pneumonia severity evaluation |
