| 摘要: |
| 手足口病(HFMD)是一种以发热、手足皮疹及口腔疱疹为主要特点的感染性疾病,可由多种肠道病毒引起,5岁以下儿童为易感人群,感染高峰在夏秋季节。大多数预后良好,但少部分由肠道病毒71型(EV71)感染所致的手足口病可出现严重的并发症,如无菌性脑膜炎、脑干脑炎、急性弛缓性麻痹、急性肺水肿和心肌炎等,严重可致死亡。随着脊髓灰质炎病毒的消灭,EV71已然成为目前最普遍的嗜神经性的肠道病毒,尚无有效的治疗及预防方法,已经成为整个亚太地区公共卫生的一大难题。 |
| 关键词: |
| DOI：10.13407/j.cnki.jpp.1672-108X.2018.10.015 |
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| 基金项目: |
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| Research Progress of Immune Mechanism and Nervous System Injury Mechanism of Enterovirus 71 Infection |
| Jiang Xue, Xu Hongmei |
| (Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China) |
| Abstract: |
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