| 摘要: |
| 目的:观察以体质辨识为基础的中医健康管理联合运脾和胃固表汤对儿童肺脾气虚型腺样体肥大( AH) 的临床疗效。
方法:选取我院2022 年7 月至2023 年12 月收治的肺脾气虚型AH 患儿120 例( 包括气虚质50 例、痰湿质51 例、阳虚质
19 例),按随机数表法分为西药组(采用孟鲁司特钠咀嚼片和糠酸莫米松鼻喷剂联合中药安慰剂治疗)、中药组(采用运脾和胃
固表汤治疗)和联合组(采用以体质辨识为基础的中医健康管理联合运脾和胃固表汤治疗)。观察3 组患儿临床疗效,记录腺
样体(A)厚度/ 鼻咽腔(N)宽度比值,并分别于治疗2、4 周及停药1、3 个月后记录中医主要证候/ 次要证候积分、阻塞性睡眠呼
吸暂停18 项生活质量调查量表(OSA-18)评分。结果:西药组、中药组、联合组总有效率分别为75. 00%、82. 50%、97. 50%( P<
0. 05)。3 组治疗后A/ N 比值、中医主要证候/ 次要证候积分均低于治疗前(P<0. 05);3 组治疗2、4 周及停药1,3 个月后OSA-18
评分均低于治疗前(P<0. 05),且中药组低于西药组(P<0. 05),联合组低于另两组(P<0. 05)。结论:以体质辨识为基础的中医
健康管理联合运脾和胃固表汤可有效提高临床疗效,降低A/ N 比值,并改善肺脾气虚型AH 患儿各维度的生活质量,且用药安
全性较高,值得临床推广应用。 |
| 关键词: 体质辨识 中医健康管理 运脾和胃固表汤 肺脾气虚 腺样体肥大 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2025.12.002 |
|
| 基金项目:2022 年成都市医学科研课题立项项目,编号2022157。 |
|
| Clinical Randomized Controlled Study on the Treatment of Adenoid Hypertrophy in Children withTraditional Chinese Medicine Health Management Based on Physique Identification Combined with YunpiHewei Gubiao Decoction |
| Leng Xianmei, Zhao Juan, Pu Juan, Cao Yanqin, Wang Binjie |
| (Chengdu Pidu District Hospital of Traditional Chinese
Medicine, Chengdu 611730, China) |
| Abstract: |
| Objective: To evaluate the clinical efficacy of traditional Chinese medicine health management based on physique
identification combined with Yunpi Hewei Gubiao decoction in the treatment of children with adenoid hypertrophy (AH) of lung, spleen
and Qi deficiency type. Methods: A total of 120 children with AH of lung, spleen and Qi deficiency type (including 50 cases of Qi
deficiency type, 51 cases of phlegm-dampness type, and 19 cases of Yang deficiency type) admitted into our hospital from Jul. 2022 to
Dec. 2023 were extracted to be randomly divided into the Western medicine group (treated with bromelast sodium chewable tablets and
mometasone furoate nasal spray combined with the placebo of traditional Chinese medicine), traditional Chinese medicine group (treated
with Yunpi Hewei Gubiao decoction), and combined group (treated with traditional Chinese medicine health management based on
physique identification combined with Yunpi Hewei Gubiao decoction). The clinical efficacy of three groups was observed, and the ratio
of the thickness of adenoids (A) to the width of nasopharyngeal cavity (N) was recorded. The main symptoms/ secondary symptoms
scores of traditional Chinese medicine syndromes, scores of Quality of Life for Children with Obstructive Sleep Apnea 18 Items (OSA-18)
were recorded at 2 and 4 weeks of treatment, and 1 and 3 months after drug withdrawal. Results: The total effective rates of Western
medicine group, traditional Chinese medicine group, and combined treatment group were respectively 75. 00%, 82. 50%, and 97. 50%
(P< 0. 05). After treatment, the A/ N ratios and scores of main symptoms/ secondary symptoms of traditional Chinese medicine
syndromes in three groups were lower than those before treatment (P<0. 05). At 2 and 4 weeks of treatment, and 1 and 3 months after
drug withdrawal, the OSA-18 scores of three groups were lower than those before treatment (P <0. 05), and the traditional Chinese
medicine group was lower than the Western medicine group (P<0. 05), and the combined group was lower than the other two groups
(P<0. 05). Conclusion: Traditional Chinese medicine health management based on physique identification combined with Yunpi Hewei
Gubiao decoction can effectively enhance clinical efficacy, reduce the A/ N ratio, and improve the quality of life in children with AH of
lung, spleen and Qi deficiency type. The therapeutic regimen demonstrates a favorable safety profile and merits broader clinical adoption
and utilization. |
| Key words: physique identification traditional Chinese medicine health management Yunpi Hewei Gubiao decoction lung, spleen
and Qi deficiency type adenoid hypertrophy |
