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基于围产期新生儿肺出血的危险因素建构列线图预测模型及早期药 物防治策略
王钟,黄玮玲,余洁,王娴,余燕,朱天娇
((咸宁市中心医院/ 湖北科技学院附属第一医院,湖北咸宁 437100))
摘要:
目的:探讨围产期新生儿肺出血(NPH)的独立危险因素并构建列线图。方法:选取2016 年6 月至2021 年6 月我院新生 儿科生后24 小时内入院的153 例新生儿,采用logistic 回归分析筛选围产期NPH 独立危险因素;以R 软件构建预测围产期 NPH 的列线图。结果:极低出生体质量儿(VLBW)、小于胎龄儿(SGA)、动脉导管未闭(PDA)、低体温、产时酸中毒是围产期发 生NPH 的独立危险因素。结论:基于独立危险因素构建列线图可预测围产期NPH 的发生,有助于临床早期识别与干预。
关键词:  围产期  新生儿肺出血  独立危险因素  列线图
DOI:doi:10.13407/j.cnki.jpp.1672-108X.2026.07.007
基金项目:咸宁市中心医院/ 湖北科技学院附属第一医院科研项目,编号2021XYB014。
Construction of Nomogram Prediction Model Based on Risk Factors for Neonatal Pulmonary HemorrhageDuring Perinatal Periods and Early Prevention Strategies
Wang Zhong, Huang Weiling, Yu Jie, Wang Xian, Yu Yan, Zhu Tianjiao
((Xianning Central Hospital / the First Affiliated Hospital of Hubei University of Science and Technology, Hubei Xianning 437100, China))
Abstract:
Objective: To probe into the independent risk factors for neonatal pulmonary hemorrhage (NPH) during perinatal period and construct the nomogram. Methods: From Jun. 2016 to Jun. 2021, totally 153 newborns admitted into the Neonatal Department of our hospital within 24 h of birth were extracted. Logistic regression analysis was applied to screen for independent risk factors for perinatal NPH. R software was applied to construct a nomogram for predicting perinatal NPH. Results: Very low birth weight infant (VLBW), small forgestational age (SGA), patent ductus arteriosus (PDA), hypothermia, and prenatal acidosis were independent risk factors for perinatal NPH. Conclusion: The nomogram constructed based on independent risk factors can predict perinatal NPH, which is helpful for early clinical identification and intervention.
Key words:  perinatal period  neonatal pulmonary hemorrhage  independent risk factors  nomogram

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