| 摘要: |
| 目的：比较3%高渗盐水、生理盐水鼻腔冲洗辅助治疗儿童上气道咳嗽综合征的近期疗效。方法：选择2014年3月至2015年11月我院儿科及耳鼻喉科门诊诊断为上气道咳嗽综合征（UACS）的患儿126例，按随机数表法分为A、B、C三组：A组37例采用常规治疗，即根据原发病采用抗感染、抗过敏等治疗，同时避免接触过敏原；B组、C组在A组基础上，加用鼻腔冲洗护理器对鼻腔进行冲洗，B组46例采用3%高渗盐水，C组43例采用生理盐水。三组患儿均治疗2周，采用视觉模拟量表（VAS）判断疗效。结果：治疗后，A、B、C三组VAS评分分别为（3.14±1.34）分、（2.33±0.92）分、（2.47±0.98）分，B组、C组均低于A组（t分别为3.399、2.769，P均<0.01），而B组与C组比较差异无统计学意义（t=0.607，P>0.05）。结论：盐水鼻腔冲洗辅助治疗儿童上气道咳嗽综合征有较好的临床效果，3%高渗盐水与生理盐水近期疗效相当，因此，建议临床优先选用生理盐水。 |
| 关键词: 3%高渗盐水 生理盐水 鼻腔冲洗 儿童 上气道咳嗽综合征 |
| DOI：10.13407/j.cnki.jpp.1672-108X.2017.07.009 |
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| 基金项目: |
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| The Short-term Therapeutic Effect of Two Concentration of Sodium Chloride in Nasal Irrigation as an Adjunctive Treatment of Upper Airway Cough Syndrome in Children |
| Chen Guifeng, Sheng Weiguo, Lai Yusheng, Lu Xiangyun |
| (The First People’s Hospital of Jiashan, Zhejiang Jiaxing 314100, China) |
| Abstract: |
| Objective: To compare the short-term therapeutic effect of 3% and 0.9% sodium chloride nasal irrigation as an adjunctive treatment of upper airway cough syndrome in children. Methods: According to the visiting time, a total of 126 patients with upper airway cough syndrome were enrolled. Patients were classified into three groups. Groups A included 37 cases was treated with antibiotic or anti-allergy medications, they were also recommended to avoid contact with allergens. On the basis of standard treatment, group B included 46 cases received nasal irrigation with 3% hypertonic saline solution, while groups C included 43 cases was adminisered with 0.9% saline solution. This study investigated the effectiveness of 2 weeks of nasal irrigation by evaluating visual analog scale (VAS) scores. Results: The VAS scores in the group A and B were both lower than that in the group A (t=3.399, 2.769, P<0.01). No significant differences were detected between group B and group C (t=0.607, P>0.05). Conclusion: Nasal irrigation is an effective adjuvant treatment for upper airway cough syndrome in children. The short-term therapeutic effect of nasal irrigation with 3% hypertonic saline solution is not superior to that with 0.9% saline solution. |
| Key words: 3% hypertonic saline 0.9% saline nasal irrigation upper airway cough syndrome |
